Paul Casey carded a triple bogey for the second day running but unlike on day two, was unable to bounce back with five birdies in succession.
Koepka takes home $2.16 million, the largest single-day earnings in golf.
It also put him squarely in the mix to capture his first major.
The final round of the 117th U.S.
Koepka is a major champion. The last was Henrik Stenson at Troon past year when he stole the Claret Jug from Phil Mickelson, who opened with a 63.
Brooks Koepka is in position to win his first major title. (I walked every hole with Thomas on Saturday, it was fun, more on that here.) Thomas got the headlines and the attention, but it was Harman taking control as the afternoon wore on - posting a more-than-solid 67 of his own to lead by one.
Then there was the Par-5 18th hole. Harman was 13 under until those back-to-back bogeys derailed him. What slowed him on Saturday was a triple bogey on the third hole, but conditions were so tough that Woods shot even-par 71 and still increased his lead to 10 shots.
Dodgers' Yasiel Puig suspended one game, fined for obscene gesture
Jose Abreu went 3-for-4 and Avisail Garcia had a two-run double as Chicago won its second straight after dropping nine of 11. Zack Greinke, who was staked to a 6-0 lead in the third, went 5⅔ innings and allowed five runs, all unearned, and five hits.
Scottie Scheffler is the low amateur for this year's U.S. Open. He started to find form in a tie for ninth at the WGC-Dell Technologies Match Play in March, placed T-11 at the Masters and finished runner-up at the Valero Texas Open.
Only six players had ever reached 10-under par at any point in a U.S. Open in the 116 previous championships. He still built a six-shot lead through 36 holes, despite hitting his tee shot into the ocean on the 18th hole and salvaging bogey. His best finish at the U.S. Open was third in 2001. Going into the final round, 42 players were still under par.
The 20-year-old Scheffler birdied No. 18 to finish off a 1-over 73.
The 117th U.S. Open was supposed to be a big hitter's major.
Thomas, who was tied for the lead at the time at 9-under, chose to go for the green from a little over 300 yards out. The 21-year-old South Korean became the youngest Players Championship victor in history last month.
Tommy Fleetwood, who played alongside Koepka and closed with a 72 to finish fourth, played the Challenge Tour a year before Koepka arrived.
The buddies who shared a house near Erin Hills also shared the misery after a wind-swept final round in which they never got themselves into the mix.
Lopez and Pouille reach the title match — ATP Stuttgart
Zverev, the sixth seed, appeared the stronger server and took the first set tie-break as Lopez found the net too often. Lucas Pouille joins Lopez in the final four as he beat Philipp Kohlschreiber, 6-4, 2-6, 6-3.
"I'll get some sleep and then come out and make a plan", he said. Two other guys that can go low, and they'll need it as they're five back at 7 under, are Brandt Snedeker and Bill Haas.
Three pars later, it was all over.
Jason Day followed up a 79 in the first round with a 75 in round two, Rory McIlroy was always up against it after a 78 on Thursday and although he shot one under on Friday he was well short of the cut.
"It looks as though the weather conditions are going to be a lot more challenging today at Erin Hills", Kite said. But Spieth might take some positives moving forward from his final round after having an up-and-down weekend. He shot 81 the next day in a blustery wind.
Thomas became the fifth player to shoot 63 in the U.S. Open, and the first with a score of 9 under.
The flag commemorates the late Arnold Palmer's win at the 1960 U.S. Open at Cherry Hills.
Justin wasn't the only one who tore Erin Hills a new one; pretty much everyone did.
There were early clues that the wind could level the playing field in some of the first groups to tee off on Sunday.
Atari's rumored new game console is reportedly PC-based
Brand licensing has also been more of a priority, with the Atari name planned for use in the upcoming Blade Runner 2049 film. That mini-retro console was a big hit despite only coming with 30 games and having wired controllers with short cables.